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These patients may experience a blunted or impeded response to the intranasal medication

Whereas the first randomized, double-blind, cross-over study with bilateral cathodal cerebellar stimulation showed no effect on essential tremor [155], the second study in which anodal tDCS was applied over the dorsolateral prefrontal cortex showed an improvement in ADL (i.e., Activities of Daily Living) scores and TETRAS (i.e., The Essential Tremor Rating Assessment Scale) scores [211]

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doi: 10.1007/s12264-022-00861-6 76 GossageLEisenTMaherER

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